C-176

  • 1 lab in 1 country
  • Funders: Chiesi Farmaceutici and 7 more
  • Cells1

Outcomes

1

Senescence-associated secretory phenotype (SASP)

downin human cells1

1 study
  1. C-176 decreases senescence-associated secretory phenotype (SASP) in human cells.

    “Senescence-associated secretory phenotype productions were increased in COPD and were attenuated by JAK-STAT or cGAS-STING pathway inhibitors (baricitinib or C-176).”

    Cellsin COPD bronchial epithelial cells

    IFN-Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease

    American journal of respiratory cell and molecular biology1 Dec 2025

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