C-176
- 1 lab in 1 country
- Funders: Chiesi Farmaceutici and 7 more
- Cells1
Outcomes
1Senescence-associated secretory phenotype (SASP)
downin human cells1
1 study
Senescence-associated secretory phenotype (SASP)
downin human cells1
C-176 decreases senescence-associated secretory phenotype (SASP) in human cells.
“Senescence-associated secretory phenotype productions were increased in COPD and were attenuated by JAK-STAT or cGAS-STING pathway inhibitors (baricitinib or C-176).”
Cellsin COPD bronchial epithelial cells
IFN-Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease
American journal of respiratory cell and molecular biology1 Dec 2025
Latest
1 in 12 monthsAmerican Journal of Respiratory Cell and Molecular Biology
IFN-Mediated Bronchial Epithelium Cellular Senescence in Chronic Obstructive Pulmonary Disease
Experiments in human cellsCellular senescence