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BRAZILIN-7-ACETATE

Intervention

1 paper3 findings

PubChem

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 2 more
  • Cells1

Outcomes

3

Proteostasis

upin worms1

1 study

  1. BRAZILIN-7-ACETATE improves proteostasis in worms.

    “preventing the accumulation of α-Syn clumps”

    Model organismsin Caenorhabditis elegans model

    Brazilin-7-acetate, a novel potential drug of Parkinson's disease, hinders the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress

    European journal of medicinal chemistry23 Nov 2023

More on Proteostasis

Behavior disorder

upin worms1

1 study

  1. BRAZILIN-7-ACETATE improves behavior disorder in worms.

    “improving behavior disorder”

    Model organismsin Caenorhabditis elegans model

    Brazilin-7-acetate, a novel potential drug of Parkinson's disease, hinders the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress

    European journal of medicinal chemistry23 Nov 2023

Lifespan

upin worms1

1 study

  1. BRAZILIN-7-ACETATE extends lifespan in worms.

    “increasing lifespan”

    Model organismsin Caenorhabditis elegans model

    Brazilin-7-acetate, a novel potential drug of Parkinson's disease, hinders the formation of α-synuclein fibril, mitigates cytotoxicity, and decreases oxidative stress

    European journal of medicinal chemistry23 Nov 2023

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