Bone marrow mononuclear cells

1. Bone marrow mononuclear cells improve left ventricular function in humans.

   “Only modest improvements in left ventricular function were shown in early clinical trials employing mesenchymal stromal cells and bone marrow-derived mononuclear cells”

   Reviewearly clinical trials

   Regenerative and molecular therapies for myocardial repair (Review)

   Medicine international·3 Jun 2026

1. Bone marrow mononuclear cells protect against hepatocellular carcinoma in mice.

   “anti-cancer capability, in particular that against melanoma as well as hepatocellular carcinoma, and lifespan-extending property of Eklf(K74R) mice could be transferred to wild-type mice”

   Animals

   Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells

   eLife·25 Jan 2024Preprint

More on Hepatocellular carcinoma

1. Bone marrow mononuclear cells protect against melanoma in mice.

   “anti-cancer capability, in particular that against melanoma as well as hepatocellular carcinoma, and lifespan-extending property of Eklf(K74R) mice could be transferred to wild-type mice”

   Animals

   Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells

   eLife·25 Jan 2024Preprint

More on Melanoma

1. Bone marrow mononuclear cells extend lifespan in mice.

   “lifespan-extending property of Eklf(K74R) mice could be transferred to wild-type mice via transplantation of their bone marrow mononuclear cells”

   Animals

   Long-term Hematopoietic Transfer of the Anti-Cancer and Lifespan-Extending Capabilities of A Genetically Engineered Blood System by Transplantation of Bone Marrow Mononuclear Cells

   eLife·25 Jan 2024Preprint