Blocking TpfeRNAb

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Cancer Institute and 2 more
  • Cells1

Outcomes

2

Telomerase activity

upin human cells1

1 study
  1. Blocking TpfeRNAb increases telomerase activity in human cells (tenfold).

    “boosted telomerase activity by tenfold”

    Cellsin senescent NHBE cells

    TERT PfeRNA regulates telomere length during cellular senescence of normal human bronchial epithelial cells

    Scientific reports1 Jul 2025

More on Telomerase activity

Telomere length

upin human cells1+18%

1 study
  1. Blocking TpfeRNAb increases telomere length in human cells (+18%).

    “Blocking TpfeRNAb in senescent cells increased telomere length by 18%”

    Cellsin senescent NHBE cells

    TERT PfeRNA regulates telomere length during cellular senescence of normal human bronchial epithelial cells

    Scientific reports1 Jul 2025

More on Telomere length

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