Bifidobacterium adolescentis

2 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab

Humans1
Animals1

Outcomes

4

Prostaglandin E2

downin mice1

1 study

Bifidobacterium adolescentis decreases prostaglandin E2 in mice.
“suppressed the prostaglandin E2 (PGE2) and affected collagen deposition”
Animalsbleomycin-induced pulmonary fibrosis
B. adolescentis alleviates inflammation and suppresses PGE2 through remodling gut microbiota to attenuate pulmonary fibrosis in aging mice
NPJ science of food24 Nov 2025

More on Prostaglandin E2

Inflammation

downin mice1

1 study

Bifidobacterium adolescentis decreases inflammation in mice.
“B. adolescentis alleviated inflammatory responses by enhancing the gut barrier”
Animalsbleomycin-induced pulmonary fibrosis
B. adolescentis alleviates inflammation and suppresses PGE2 through remodling gut microbiota to attenuate pulmonary fibrosis in aging mice
NPJ science of food24 Nov 2025

More on Inflammation

Pulmonary fibrosis

downin mice1

1 study

Bifidobacterium adolescentis decreases pulmonary fibrosis in mice.
“intervention of B. adolescentis attenuated the degree of pulmonary fibrosis in aging mice to a state similar to that of young mice”
Animalsbleomycin-induced pulmonary fibrosis
B. adolescentis alleviates inflammation and suppresses PGE2 through remodling gut microbiota to attenuate pulmonary fibrosis in aging mice
NPJ science of food24 Nov 2025

More on Pulmonary fibrosis

Brachial-ankle pulse wave velocity

downin silico1

1 study

Bifidobacterium adolescentis decreases brachial-ankle pulse wave velocity in silico (P = 1.81×10-4).
“higher abundance of Bifidobacterium adolescentis (P-value:1.81×10-4) and Lachnospiraceae (P-value:2.88×10-5) associated with lower baPWV.”
In silico
MICROBIOTA COULD REDUCE THE BRACHIAL-ANKLE PULSE WAVE VELOCITY TO PROTECT FROM CARDIOVASCULAR DISEASE
GSA 2024 abstract31 Dec 2024

More on Brachial-ankle pulse wave velocity

Latest

1 in 12 months

NPJ Science of Food25 Nov

B. adolescentis alleviates inflammation and suppresses PGE2 through remodling gut microbiota to attenuate pulmonary fibrosis in aging mice

Experiments in micePulmonary fibrosis

GSA 2024 Abstract1 Jan

MICROBIOTA COULD REDUCE THE BRACHIAL-ANKLE PULSE WAVE VELOCITY TO PROTECT FROM CARDIOVASCULAR DISEASE

Mendelian randomisation in peopleMicrobiome composition