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Avfpsivgr

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Sichuan Province Science and Technology Support Program
  • Model organisms1

Outcomes

3

Locomotor behavior

upin flies1

1 study

  1. Avfpsivgr improves locomotor behavior in flies.

    “improved locomotor behavior, and raised the ATP and dopamine levels at all ages in PINK1B9 mutant flies”

    Model organismsin PINK1B9 mutant flies

    Isolation and Characterization of Earthworm Peptides with Neuroprotective Effects in Parkinson's Disease Models

    Molecules (Basel, Switzerland)28 Apr 2025

Lifespan

upin flies1

1 study

  1. Avfpsivgr extends lifespan in flies.

    “Furthermore, GYSFTTTAER and AVFPSIVGR extended the lifespan, improved locomotor behavior, and raised the ATP and dopamine levels at all ages in PINK1B9 mutant flies”

    Model organismsin PINK1B9 mutant flies

    Isolation and Characterization of Earthworm Peptides with Neuroprotective Effects in Parkinson's Disease Models

    Molecules (Basel, Switzerland)28 Apr 2025

Cell viability

upin human cells1

1 study

  1. Avfpsivgr improves cell viability in human cells.

    “Two peptides (GYSFTTTAER and AVFPSIVGR) isolated from earthworms improved cell viability of the SH-SY5Y human neuroblastoma cell line treated with 1-methyl-4-phenyl-1,2,3-tetrahydropyridinehydrochloride (MPP+)”

    Cellsin MPP+-treated cells

    Isolation and Characterization of Earthworm Peptides with Neuroprotective Effects in Parkinson's Disease Models

    Molecules (Basel, Switzerland)28 Apr 2025

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