Ava@hm/trop2

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Apoptosis

upin animals1

1 study
  1. Ava@hm/trop2 induces apoptosis.

    “Ava@HM/Trop2 achieves efficient tumor targeting, robust tumor cell apoptosis, and improved therapeutic outcomes.”

    Animalsin vitro and in vivo

    A multifunctional nanozyme integrating panoptosis induction and T-cell metabolic reprogramming to augment the efficacy of PD-1 inhibitors

    Colloids and surfaces. B, Biointerfaces22 Dec 2025

More on Apoptosis

Anti-tumor immunity

upin animals1

1 study
  1. Ava@hm/trop2 increases anti-tumor immunity.

    “This process activates the cGAS-STING pathway, remodels immunosuppressive TME, mitigates lipid-induced T cell senescence, and synergizes with PD-1 blockade to potentiate anti-tumor immunity.”

    Animalsin vitro and in vivo

    A multifunctional nanozyme integrating panoptosis induction and T-cell metabolic reprogramming to augment the efficacy of PD-1 inhibitors

    Colloids and surfaces. B, Biointerfaces22 Dec 2025

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