Ava@hm/trop2
1 paper2 findings
- 1 lab in 1 country
- Funder: National Natural Science Foundation of China
- Animals1
Outcomes
2Apoptosis
upin animals1
1 study
Apoptosis
upin animals1
Ava@hm/trop2 induces apoptosis.
“Ava@HM/Trop2 achieves efficient tumor targeting, robust tumor cell apoptosis, and improved therapeutic outcomes.”
Animalsin vitro and in vivo
Colloids and surfaces. B, Biointerfaces22 Dec 2025
Anti-tumor immunity
upin animals1
1 study
Anti-tumor immunity
upin animals1
Ava@hm/trop2 increases anti-tumor immunity.
“This process activates the cGAS-STING pathway, remodels immunosuppressive TME, mitigates lipid-induced T cell senescence, and synergizes with PD-1 blockade to potentiate anti-tumor immunity.”
Animalsin vitro and in vivo
Colloids and surfaces. B, Biointerfaces22 Dec 2025
Latest
1 in 12 monthsColloids and Surfaces B, Biointerfaces
A multifunctional nanozyme integrating panoptosis induction and T-cell metabolic reprogramming to augment the efficacy of PD-1 inhibitors
Experiments in animalsBlood and immune system