Ascr#10
- 1 lab in 1 country
- Funders: National Institute of General Medical Sciences and 3 more
- Model organisms2
Outcomes
2Germline progenitor cells
upin worms1
1 study
Germline progenitor cells
upin worms1
Ascr#10 increases germline progenitor cells in worms.
“upon encountering ascr#10 adult hermaphrodites increase this cell population”
Model organismsgermlinefemales
Developmental biology13 Mar 2026
Oocyte precursor proliferation
upin worms1
1 study
Oocyte precursor proliferation
upin worms1
Ascr#10 increases oocyte precursor proliferation in worms.
“We found that the male pheromone promotes proliferation of oocyte precursors by upregulating LAG-2”
Model organismsgermline
bioRxiv : the preprint server for biology9 May 2024Preprint
Latest
1 in 12 monthsbioRxiv
The roles of TGFβ and serotonin signaling in regulating proliferation of oocyte precursors and germline aging
Preprint: experiments in wormsTGF-β signalling
Cell Reports
Early pheromone perception remodels neurodevelopment and accelerates neurodegeneration in adult C. elegans
Experiments in model organismsMechanisms
Molecular Biology and Evolution
A Caenorhabditis elegans Male Pheromone Feminizes Germline Gene Expression in Hermaphrodites and Imposes Life-History Costs
Experiments in model organismsMechanisms
bioRxiv
A C. elegans male pheromone feminizes germline gene expression in hermaphrodites and imposes life-history costs
Preprint: experiments in model organismsMechanisms
Developmental Biology
Serotonergic signaling plays a deeply conserved role in improving oocyte quality
Experiments in model organismsInterventions
PNAS
A male pheromone that improves the quality of the oogenic germline
Experiments in model organismsMechanisms