AgingResearch.NewsJoin free

Arthroplasty

Arthroplasty has been studied in 10 papers since 2021: 8 observational studies in people, 2 reviews; 1 in the past year. The newest paper, Oct 27, 2025: “A prospective pilot study on plasma amyloid beta oligomers and postoperative delirium”.

Exposure

10 papers study it3 findingsUpdated

See all 10

“Group B from 52.6% to 72.2% (p = 0.001), reflecting enhanced lateral stability.”
Kinesiological Analysis Using Inertial Sensor Systems: Methodological Framework and Clinical Applications in Pathological GaitSensors (Basel, Switzerland)2025doi:10.3390/s25144435

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 3 independent labs in 2 countries
  • Funders: Korea Health Industry Development Institute and 6 more
  • Humans8

What did studies of Arthroplasty find?

2

Studies of Arthroplasty measured 2 outcomes; the most studied are plasma amyloid-beta oligomers (1 study) and lateral stability (1).

Plasma amyloid-beta oligomers

no changein humans1

1 study

  1. Arthroplasty has no effect on plasma amyloid-beta oligomers in humans.

    “There was no significant perioperative change in MDS-Oaβ, suggesting surgery or anesthesia did not alter the plasma Aβ oligomerization tendency.”

    Humansperioperativen = 22

    A prospective pilot study on plasma amyloid beta oligomers and postoperative delirium

    Frontiers in medicine

More on Plasma amyloid-beta oligomers

Lateral stability

upin humans1

1 study

  1. Arthroplasty improves lateral stability in humans (52.6% to 72.2% (p = 0.001)).

    “Group B from 52.6% to 72.2% (p = 0.001), reflecting enhanced lateral stability.”

    Human trialarthroplastyn = 34

    Kinesiological Analysis Using Inertial Sensor Systems: Methodological Framework and Clinical Applications in Pathological Gait

    Sensors (Basel, Switzerland)

What is Arthroplasty linked with?

1

Studies link Arthroplasty with 1 measure, most often frailty index (1 study).

Frailty index

no changein humans1

1 study

  1. Frailty index is associated with arthroplasty in humans (not significantly affect risk of experiencing KA/HA except in female participants undergoing HA (hazard ratio 1.29, 95% CI 1.04-1.61)).

    “Regardless of surgical site, frailty index scores did not significantly affect risk of experiencing KA/HA except in female participants undergoing HA (hazard ratio 1.29, 95% CI 1.04-1.61, P = 0.02).”

    Humans~9 yearsn = 4,753

    Association of Frailty With Risk of Osteoarthritis Development, Progression, and Worse Clinical Outcomes in Older Adults

    The Journal of rheumatology

More on Frailty index

Funding

12 grants since 2017

National Institute on AgingUS$4.7mJapan Society for the Promotion of ScienceJP¥16.1mUS Department of Veterans Affairs

Latest

Related