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ANTI-TGF-BETA-1 neutralizing antibody

Intervention

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Cells1

Outcomes

2

Mitochondrial function

upin human cells1

1 study

  1. ANTI-TGF-BETA-1 neutralizing antibody improves mitochondrial function in human cells.

    “Blockade of TGF-β1 signalling using an anti-TGF-β1 neutralizing antibody alleviated the lean hASC senescence and mitochondrial dysfunction induced by the obese hASC-derived matrix.”

    Cellsinduced by the obese hASC-derived matrixvisceral white adipose tissue

    Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue

    Stem cell research & therapyOct 8, 2023

Cellular senescence

downin human cells1

1 study

  1. ANTI-TGF-BETA-1 neutralizing antibody decreases cellular senescence in human cells.

    “Blockade of TGF-β1 signalling using an anti-TGF-β1 neutralizing antibody alleviated the lean hASC senescence and mitochondrial dysfunction induced by the obese hASC-derived matrix.”

    Cellsinduced by the obese hASC-derived matrixvisceral white adipose tissue

    Blockade of TGF-β signalling alleviates human adipose stem cell senescence induced by native ECM in obesity visceral white adipose tissue

    Stem cell research & therapyOct 8, 2023

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