Anti-obesity agents

Anti-obesity agents improve six-minute walk test distance in humans (MD: 13.95 [95% CI: 5.84 to 22.07]).

“Three studies reported objective physical function, suggesting modest gains relative to control (Six-Minute Walk Test MD: 13.95, [95% CI: 5.84 to 22.07]”

Reviewoverweight or obesity

Effect of Obesity Management Medications on Physical Function: A Systematic Review and Meta-analysis

ADA Scientific Sessions 2026 abstract·5 Jun 2026

Anti-obesity agents improve impact of Weight on Quality-of-Life physical function in humans (MD: 5.58 [95% CI: 4.24 to 6.92]).

“Impact of Weight on Quality-of-Life (MD: 5.58, [95% CI: 4.24 to 6.92], I2 = 65.8%, p < 0.01) self-report measures.”

Reviewoverweight or obesityn = 25,068

Effect of Obesity Management Medications on Physical Function: A Systematic Review and Meta-analysis

ADA Scientific Sessions 2026 abstract·5 Jun 2026

Anti-obesity agents improve short-Form-36 physical function in humans (MD: 1.76 [95% CI: 1.20 to 2.32]).

“self-reported physical function improved with OMMs on both the Short-Form-36 (MD: 1.76 [95% CI: 1.20 to 2.32], I2 = 62.5%, p < 0.01)”

Reviewoverweight or obesityn = 25,068

Effect of Obesity Management Medications on Physical Function: A Systematic Review and Meta-analysis

ADA Scientific Sessions 2026 abstract·5 Jun 2026