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Anastrozole

Intervention

1 paper2 findings

PubChemChEBIMeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Arizona Department of Health Services and 6 more
  • Animals1

Outcomes

2

Cognitive function

no changein rats1

1 study

  1. Anastrozole has no effect on cognitive function in rats.

    “Anastrozole alone did not impact performance on any cognitive measure.”

    Animalsin young adult ovariectomized ratsfemales

    Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats

    Steroids23 Aug 2014

Cognitive impairment

downin rats1

1 study

  1. Anastrozole protects against cognitive impairment in rats.

    “Further, androstenedione did not induce memory deficits when co-administered with the aromatase inhibitor, anastrozole”

    Animalsin androstenedione-treated young adult ovariectomized ratsfemales

    Pharmacological blockade of the aromatase enzyme, but not the androgen receptor, reverses androstenedione-induced cognitive impairments in young surgically menopausal rats

    Steroids23 Aug 2014

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