Amyloid-beta 42

1 paper1 finding

1 lab in 1 country

Funders: Brain Research Foundation and 4 more

Model organisms1

Outcomes

1

RISC-bound sRNA 6mer seed toxicity

upin cells1

1 study

Amyloid-beta 42 increases RISC-bound sRNA 6mer seed toxicity in cells.
“RISC-bound sRNAs show a shift to more toxic 6mer seeds compared to controls.”
Cellscells exposed to Aβ42 oligomersoligomers
Death Induced by Survival gene Elimination (DISE) is correlated with neurotoxicity in Alzheimer’s disease and aging
bioRxiv (Cold Spring Harbor Laboratory)Sep 10, 2022Preprint

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