Agarose oligosaccharides

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Fundamental Research Funds for the Provincial Universities of Zhejiang and 1 more

Model organisms1

Outcomes

4

Acetobacter persici

upin flies1

1 study

Agarose oligosaccharides increase Acetobacter persici in flies.
“evidenced by the significant increase in Acetobacter persici and acetic acid contents.”
Model organismsmales
Agarose oligosaccharides balance intestinal stem cell homeostasis in aging D. melanogaster by regulating the Acetobacter persici-acetic acid-JAK/STAT signaling axis
Microbiome11 Mar 2026

More on Acetobacter persici

Intestinal epithelial barrier dysfunction

downin flies1

1 study

Agarose oligosaccharides decrease intestinal epithelial barrier dysfunction in flies.
“alleviated intestinal epithelial barrier dysfunction.”
Model organismsmales
Agarose oligosaccharides balance intestinal stem cell homeostasis in aging D. melanogaster by regulating the Acetobacter persici-acetic acid-JAK/STAT signaling axis
Microbiome11 Mar 2026

More on Intestinal epithelial barrier dysfunction

Oxidative stress and ROS signalling

downin flies1

1 study

Agarose oligosaccharides decrease oxidative stress and ROS signalling in flies.
“supplementation with AOS significantly extended mean and maximum lifespan, reduced oxidative stress, and alleviated intestinal epithelial barrier dysfunction.”
Model organismsmales
Agarose oligosaccharides balance intestinal stem cell homeostasis in aging D. melanogaster by regulating the Acetobacter persici-acetic acid-JAK/STAT signaling axis
Microbiome11 Mar 2026

More on Oxidative stress and ROS signalling

Lifespan

upin flies1

1 study

Agarose oligosaccharides extend lifespan in flies.
“supplementation with AOS significantly extended mean and maximum lifespan, reduced oxidative stress, and alleviated intestinal epithelial barrier dysfunction.”
Model organismsmales
Agarose oligosaccharides balance intestinal stem cell homeostasis in aging D. melanogaster by regulating the Acetobacter persici-acetic acid-JAK/STAT signaling axis
Microbiome11 Mar 2026

Latest

1 in 12 months

Microbiome12 Mar

Agarose oligosaccharides balance intestinal stem cell homeostasis in aging D. melanogaster by regulating the Acetobacter persici-acetic acid-JAK/STAT signaling axis

Experiments in fliesGut and microbiome