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Adipose-derived mesenchymal stromal cells

Adipose-derived mesenchymal stromal cells has been studied in 2 papers since 2023: none in people yet, 1 in animals, 1 in cells. The research so far is in animals and cells. The newest paper, Jan 15, 2025: “Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis”.

Intervention

2 papers study it3 findingsUpdated

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 2 countries
  • Funders: National Natural Science Foundation of China and 3 more
  • Animals1
  • Cells1

What did studies of Adipose-derived mesenchymal stromal cells find?

2

Studies of Adipose-derived mesenchymal stromal cells measured 2 outcomes; the most studied are physical function (1 study) and angiogenesis (1).

Physical function

upin rats1

1 study

  1. Adipose-derived mesenchymal stromal cells improve physical function in rats.

    “Moreover, ADSC-GMs significantly promoted the regeneration of bladder vessels and smooth muscle, thereby facilitating the recovery of bladder function.”

    Animalsin bladder replacementbladder12 weeksmales

    Porous gelatin microspheres implanted with adipose mesenchymal stromal cells promote angiogenesis via protein kinase B/endothelial nitric oxide synthase signaling pathway in bladder reconstruction

    Cytotherapy

Angiogenesis

upin rats1

1 study

  1. Adipose-derived mesenchymal stromal cells increase angiogenesis in rats.

    “Moreover, ADSC-GMs significantly promoted the regeneration of bladder vessels and smooth muscle, thereby facilitating the recovery of bladder function.”

    Animalsin bladder replacementbladder12 weeksmales

    Porous gelatin microspheres implanted with adipose mesenchymal stromal cells promote angiogenesis via protein kinase B/endothelial nitric oxide synthase signaling pathway in bladder reconstruction

    Cytotherapy

More on Angiogenesis

What acts on Adipose-derived mesenchymal stromal cells?

1

Studies name 1 thing that act on Adipose-derived mesenchymal stromal cells, most often rapamycin (1 study).

Rapamycin

upin human cells1

1 study

  1. Rapamycin improves adipose-derived mesenchymal stromal cells in human cells.

    “AD-MSCs displayed improved chondroprotective regenerative effects on co-cultured OA chondrocytes.”

    Cellsco-culture

    Combination of rapamycin and adipose-derived mesenchymal stromal cells enhances therapeutic potential for osteoarthritis

    Stem cell research & therapy

More on Rapamycin

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