Adenosine diphosphate
Intervention1 paper4 findingsPubChem 6022ChEBI 16761
In one mouse study, adenosine diphosphate reduces cellular senescence, the senescence-associated secretory phenotype and systemic lupus erythematosus in a lupus model, and activates AMPK signalling in macrophages.
- Animals1
Outcomes
4AMPK signalling
upin mice1Very low certainty
1 study
AMPK signalling
upin mice1Very low certainty
Adenosine diphosphate activates AMPK signalling in mice.
Animalsmacrophages
ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026
Systemic lupus erythematosus
downin mice1Very low certainty
1 study
Systemic lupus erythematosus
downin mice1Very low certainty
Adenosine diphosphate decreases systemic lupus erythematosus in mice.
Animalsin SLE mouse model
ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026
Senescence-associated secretory phenotype (SASP)
downin mice1Very low certainty
1 study
Senescence-associated secretory phenotype (SASP)
downin mice1Very low certainty
Adenosine diphosphate decreases senescence-associated secretory phenotype (SASP) in mice.
Animalsin SLE mouse model
ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026
Cellular senescence
downin mice1Very low certainty
1 study
Cellular senescence
downin mice1Very low certainty
Adenosine diphosphate inhibits cellular senescence in mice.
Animalsin SLE mouse model
ADP Inhibits Macrophage Senescence via the AMPK/KLF10 Pathway in Systemic Lupus Erythematosus · FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 23 Sep 2026