AC-4067

1 paper2 findings

1 lab in 1 country

Funder: National Research Foundation of Korea

Cells1

Outcomes

2

DNA damage response

downin human cells1

1 study

AC-4067 decreases DNA damage response in human cells.
“Mechanistically, DDR1 inhibition markedly reduced γH2AX protein levels, indicating suppression of persistent DNA damage signaling”
Cellsin late-passage WJ-MSCsWharton's jelly
Targeting DDR1 with novel synthesized antagonists delays cellular aging and enhances wound healing in mesenchymal stem cells
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie7 Mar 2026

More on DNA damage response

Cellular senescence

downin human cells1

1 study

AC-4067 decreases cellular senescence in human cells.
“sustained DDR1 inhibition significantly attenuated replicative senescence, as evidenced by reduced senescence-associated β-galactosidase activity”
Cellsin late-passage WJ-MSCsWharton's jelly
Targeting DDR1 with novel synthesized antagonists delays cellular aging and enhances wound healing in mesenchymal stem cells
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie7 Mar 2026

More on Cellular senescence

Latest

1 in 12 months

Biomedicine & Pharmacotherapy8 Mar

Targeting DDR1 with novel synthesized antagonists delays cellular aging and enhances wound healing in mesenchymal stem cells

Experiments in human cellsInterventions