AAV9-MEDIATED OXR1 silencing
Intervention1 paper1 finding
- Animals1
Outcomes
1Bone loss
downin mice1Very low certainty
1 study
Bone loss
downin mice1Very low certainty
AAV9-MEDIATED OXR1 silencing decreases bone loss in mice.
Animalsovariectomy-induced osteoporosisAAV9-shRNAbone
Targeting a cell regulator reduced bone loss in mice · Nature communications · 5 Sep 2026
Latest
1Nature CommunicationsAnimals
Targeting a cell regulator reduced bone loss in mice
In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.In a mouse model of osteoporosis, silencing a gene or inhibiting its protein reduced the activity of cells that break down bone.