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AAV8-Y733F

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Eye Institute and 1 more
  • Animals1

Outcomes

1

Cone rescue

upin mice1

1 study

  1. AAV8-Y733F improves cone rescue in mice.

    “Our results demonstrate that the AAV8-Y733F capsid achieved superior cone rescue compared to AAV5.”

    Animalsin BCM mouse models

    Molecular Mechanisms Limiting the Therapeutic Window of AAV Gene Therapy in Mouse Models of Blue Cone Monochromacy

    Research square7 Apr 2025Preprint

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