Aav-mediated gene therapy

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Animals1

Outcomes

2

Cognitive function

upin mice1

1 study
  1. Aav-mediated gene therapy improves cognitive function in mice.

    “AAV‐mediated gene therapy in 5xFAD/PPT1+/‐ mice decreased the Ab burden, increased life span, and improved cognitive function.”

    Animalsin 5xFAD/PPT1+/- mice

    Heterozygosity of lysosomal enzyme genes and Alzheimer's disease

    AAIC 2025 abstract23 Dec 2025

Lifespan

upin mice1

1 study
  1. Aav-mediated gene therapy extends lifespan in mice.

    “AAV‐mediated gene therapy in 5xFAD/PPT1+/‐ mice decreased the Ab burden, increased life span, and improved cognitive function.”

    Animalsin 5xFAD/PPT1+/- micebrain

    Heterozygosity of lysosomal enzyme genes and Alzheimer's disease

    AAIC 2025 abstract23 Dec 2025

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