Aav-mediated SIRT6 gene therapy
1 paper1 finding
- 1 lab in 1 country
- Funders: Hebrew University of Jerusalem and 6 more
- Animals1
Outcomes
1Age-related chromatin accessibility changes
downin mice1
1 study
Age-related chromatin accessibility changes
downin mice1
Aav-mediated SIRT6 gene therapy decreases age-related chromatin accessibility changes in mice.
“SIRT6 not only slows age-related chromatin changes but can also reverse them, rejuvenating chromatin accessibility to a youthful state.”
AnimalsAAV-mediated overexpressionlivermales
SIRT6 overexpression counteracts chromatin aging in the male murine liver
Nature communications14 May 2026
Latest
1 in 12 monthsNature Communications
SIRT6 overexpression counteracts chromatin aging in the male murine liver
Experiments in miceInterventions