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5mer peptide

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Israel Science Foundation and 1 more
  • Model organisms1

Outcomes

2

Lifespan

no changein worms1

1 study

  1. 5mer peptide has no effect on lifespan in worms.

    “while minimally affecting lifespan.”

    Model organismsin nematodes

    A short peptide protects from age-onset proteotoxicity

    Aging cellOct 27, 2023

Proteotoxicity

downin worms1

1 study

  1. 5mer peptide protects against proteotoxicity in worms.

    “We found that the 5MER peptide mitigates the toxicity that stems from both; the AD-causing Aβ peptide and a stretch of poly-glutamine”

    Model organismsin nematode models of Alzheimer's and Huntington's disease

    A short peptide protects from age-onset proteotoxicity

    Aging cellOct 27, 2023

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