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polyQ35-YFP

1 paper

Model organisms1

Latest

Aging Cell·Oct 28

A short peptide protects from age-onset proteotoxicity

Experiments in wormsInterventions

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5mer peptide1
APP1
Alzheimer's disease1
Huntington's disease1
Protein folding and chaperones1
Proteostasis1
Ubiquitin–proteasome system1
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Physical performance declines around 35, falling 30–48% below peak by 63ResearchScienceDaily and 4 more

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TIMP2 protein improves microglial debris clearance and reduces inflammatory signatures in older miceResearchScienceDaily and 3 more

Trials

Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and WomenResults posted Oct 13, 2026, Marquette University Benefits of Strength Training in Informal Caregivers of Patients With Alzheimer's DiseaseCompleted Oct 16, 2026, University of Salamanca Fisetin for Improving Vascular Function in Older Adults: A Phase II Clinical TrialPhase 2Registered Oct 13, 2026, University of Colorado, Boulder

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