11beta-hsd2 inhibitor

1 paper1 finding

1 lab in 2 countries

Funders: National Cancer Institute and 1 more

Animals1

Outcomes

1

PTGS2

downin human cells1

1 study

11beta-hsd2 inhibitor inhibits PTGS2 in human cells.
“Inhibition of 11βHSD2 activity enhanced glucocorticoid-mediated COX-2 inhibition in human lung carcinoma cells.”
Cellshuman lung carcinoma cells
Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways
PloS one26 May 2015

Latest

PLOS One26 May

Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways

Experiments in animalsMAPK/ERK signalling