10-hydroxy-2-decenoic acid
- 1 lab in 1 country
- Funders: Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas and others
- Cells1
Outcomes
4SIRT1
upin cells1
1 study
SIRT1
upin cells1
10-hydroxy-2-decenoic acid activates SIRT1 in cells.
“QBA stimulates sirtuin 1 (SIRT1), which promotes autophagy by the deacetylation of critical ATG proteins”
Cells
Neuroprotective properties of queen bee acid by autophagy induction
Cell biology and toxicology27 Aug 2021
Autophagy
upin cells1
1 study
Autophagy
upin cells1
10-hydroxy-2-decenoic acid activates autophagy in cells.
“QBA is a novel autophagy inducer that triggers autophagy in various neuronal cell lines and mouse and fly models”
Cells
Neuroprotective properties of queen bee acid by autophagy induction
Cell biology and toxicology27 Aug 2021
Parkinson's disease
downin mice1
1 study
Parkinson's disease
downin mice1
10-hydroxy-2-decenoic acid protects against Parkinson's disease in mice.
“QBA-mediated autophagy promotes neuroprotection in Parkinson's disease in vitro and in a mouse model”
AnimalsParkinson's disease
Neuroprotective properties of queen bee acid by autophagy induction
Cell biology and toxicology27 Aug 2021
Lifespan
upin flies1
1 study
Lifespan
upin flies1
10-hydroxy-2-decenoic acid extends lifespan in flies.
“extends the lifespan of Drosophila melanogaster”
Model organisms
Neuroprotective properties of queen bee acid by autophagy induction
Cell biology and toxicology27 Aug 2021