Phytotherapy Research
Mulberry compound prevented bone loss in two mouse models
Preventive dosing for six or eight weeks preserved bone in female mice after ovary removal and male mice fed a high-fat diet.Preventive dosing for six or eight weeks preserved bone in female mice after ovary removal and male mice fed a high-fat diet.
Mouse studyBones and joints
Who was studiedMice with ovariectomy- or diet-induced osteoporosis, six weeks; 8 weeks
What changedDNJ reduced trabecular bone volume loss by 47.2% in high-fat-fed mice compared with saline-treated mice
The catchBone scans included only 5–7 DNJ-treated ovariectomized mice and 6 DNJ-treated high-fat-fed mice