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1-aminobenzotriazole

Intervention

1 paper2 findings

PubChemChEBI

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 2 countries
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

2

Gingival fibroblast activity

upin cells1

1 study

  1. 1-aminobenzotriazole improves gingival fibroblast activity in cells.

    “the antioxidant 1-aminobenzotriazole (ABT) pretreatment could partially reverse this effect.”

    CellsEGFR functional inhibition

    Proteomics Insights Into Gingival Aging: The Role of Oxidative Stress and Key Signaling Pathways

    International dental journal28 Jul 2025

Cellular senescence

downin rat cells1

1 study

  1. 1-aminobenzotriazole decreases cellular senescence in rat cells.

    “This senescent-promoting effect could be enhanced by ICI 182,780 and eliminated by a cytochrome P450s inhibitor ABT”

    Cellsin H2O2- and estradiol-treated VSMCs from old ratsfemales

    Effects of estrogen on stress-induced premature senescence of vascular smooth muscle cells: a novel mechanism for the "time window theory" of menopausal hormone therapy

    Atherosclerosis19 Jan 2011

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