BMC Cardiovascular Disorders
Proteins improved cardiovascular risk prediction in metabolic syndrome
A blood-protein model better distinguished who later developed cardiovascular events, scoring 0.730 versus 0.673 for a clinical model in a validation group.A blood-protein model better distinguished who later developed cardiovascular events, scoring 0.730 versus 0.673 for a clinical model in a validation group.
Cohort · 12,308 peopleMetabolic syndrome
Who was studied12,308 people with metabolic syndrome, against the clinical PREVENT model
What changedCardiovascular prediction accuracy was higher with proteins: C-statistic 0.730 against 0.673 with the clinical PREVENT model
The catchParticipants were healthier than the broader population, potentially biasing the model’s performance