UQCRC2

Gene

1 paper3 findings

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Cells1

Effects

3

Oxidative phosphorylation

upin human cells1

1 study
  1. UQCRC2 increases oxidative phosphorylation in human cells.

    “decreased mitochondrial membrane potential, and a decline in the oxygen consumption rate for oxidative phosphorylation”

    Cellsin 3D culture, shown by knockdown

    3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation

    Journal of translational medicine20 Dec 2024

More on Oxidative phosphorylation

Mitochondrial ROS

downin human cells1

1 study
  1. UQCRC2 decreases mitochondrial ROS in human cells.

    “resulted in increased production of mitochondrial reactive oxygen species”

    Cellsin 3D culture, shown by knockdown

    3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation

    Journal of translational medicine20 Dec 2024

More on Mitochondrial ROS

Cellular senescence

downin human cells1

1 study
  1. UQCRC2 inhibits cellular senescence in human cells.

    “accelerating cell senescence”

    Cellsin 3D culture, shown by knockdown

    3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation

    Journal of translational medicine20 Dec 2024

More on Cellular senescence

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