Ucp5

1. Ucp5 decreases triglyceride in flies.

   “systemic overexpression of UCP5 can lower triglyceride levels under such dietary conditions”

   Model organismsunder high-fat diet conditions

   The role of UCP5 in cardiac aging and metabolism in Drosophila

   Biochimie·Sep 24, 2025

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1. Ucp5 extends lifespan in flies.

   “Cardiac-specific UCP5 overexpression reduced the reactive oxygen species levels within the cardiomyocyte nuclei and extended the lifespan.”

   Model organismscardiac-specific UCP5 overexpression

   The role of UCP5 in cardiac aging and metabolism in Drosophila

   Biochimie·Sep 24, 2025

1. Ucp5 decreases reactive oxygen species in flies.

   “Cardiac-specific UCP5 overexpression reduced the reactive oxygen species levels within the cardiomyocyte nuclei”

   Model organismscardiac-specific UCP5 overexpressionheart

   The role of UCP5 in cardiac aging and metabolism in Drosophila

   Biochimie·Sep 24, 2025

More on Reactive oxygen species

1. Ucp5 increases asystole in flies.

   “cardiac-specific UCP5 knockdown induced an age-dependent increase in the incidence of asystoles”

   Model organismscardiac-specific UCP5 knockdownheart

   The role of UCP5 in cardiac aging and metabolism in Drosophila

   Biochimie·Sep 24, 2025

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1. Ucp5 increases fibrillation in flies.

   “cardiac-specific UCP5 overexpression increased the incidence of fibrillation in an age-dependent trend”

   Model organismscardiac-specific UCP5 overexpressionheart

   The role of UCP5 in cardiac aging and metabolism in Drosophila

   Biochimie·Sep 24, 2025

More on Fibrillation