TRR1

1. TRR1 is required for cellular fitness in yeast cells.

   “Additionally, maintaining the liquid-like dynamic nature of Trr1 condensates was essential for cellular fitness.”

   Cells

   Trr1 (thioredoxin reductase 1) modulates ERphagy in aging via liquid-liquid phase separation

   Autophagy·31 Jul 2026

1. TRR1 activates autophagy in yeast cells.

   “Trr1 condensates participated at the phagophore assembly site during endoplasmic reticulophagy and promoted autophagosome development by affecting lipidation of the Atg8 protein.”

   Cellsduring endoplasmic reticulophagy

   Trr1 (thioredoxin reductase 1) modulates ERphagy in aging via liquid-liquid phase separation

   Autophagy·31 Jul 2026

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