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TNFRSF10

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 2 countries
  • Funders: National Eye Institute and 2 more
  • Cells1

Effects

1

CDKN2A

downin mice1

1 study

  1. TNFRSF10 decreases CDKN2A in mice.

    “in vivo studies showed upregulation of p16 and p21 by RT-PCR, WB, and immunostaining analysis in RPE/choroid of Tnfrsf10 KO mice.”

    Animalsknockoutretinal pigment epithelium/choroid

    Characterization and contribution of RPE senescence to Age-related macular degeneration in Tnfrsf10 knock out mice

    bioRxiv : the preprint server for biologyAug 6, 2023Preprint

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