SVIP

2 papers2 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: National Institute on Aging and 2 more

Humans1
Model organisms1

Effects

2

Healthspan

upin worms1

1 study

SVIP improves healthspan in worms.
“expression of the human ortholog of SVIP in the C. elegans gut causes similar physiological and phenotypic effects as Drosophila SVIP”
Model organismsexpression of human SVIP in well-fed C. elegansintestine
Human SVIP is sufficient to stimulate tubular lysosomes and extend healthspan in well-fed Caenorhabditis elegans
microPublication biology1 Nov 2024

Functional tubular lysosomes

upin worms1

1 study

SVIP induces functional tubular lysosomes in worms.
“These results demonstrate that human SVIP can induce functional TLs in C. elegans”
Model organismsexpression of human SVIP in well-fed C. elegansintestine
Human SVIP is sufficient to stimulate tubular lysosomes and extend healthspan in well-fed Caenorhabditis elegans
microPublication biology1 Nov 2024

Latest

1 in 12 months

AAIC 2025 Abstract26 Dec

SVIP: A Potential Blood‐based Biomarker for Early detection of Mild Cognitive Impairment

Case-control study of 84 peopleMild cognitive impairment

MicroPublication Biology18 Nov

Human SVIP is sufficient to stimulate tubular lysosomes and extend healthspan in well-fed Caenorhabditis elegans

Experiments in wormsLysosome