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Animals1

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Advanced Science·31 Oct

Integrative Omics Reveal Female-Specific Benefits of p16⁺ Cell Clearance in Aging Mice

Experiments in miceInterventions

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CD361
CDKN2A1
Cellular senescence1
Inflammation1
LRRFIP11
Mitochondrion1
Oxidative phosphorylation1
Liver damage1
P16+ cell ablation1
P16+ cells1
p16INK4a–RB pathway1

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Restoring Menin protein improves memory and bone mass in older mice within 30 daysResearchScienceDaily and 1 more

Trials

AKG and Brain Health in AgingPhase 2Registered 6 Oct 2026, University of Oklahoma Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)Phase 1Registered 2 Oct 2026, Vinmec Research Institute of Stem Cell and Gene Technology AI-Based Conversational Social Support for Older Adults With Heart FailureRegistered 7 Oct 2026, Chang Gung University of Science and Technology

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Topics

Mechanisms269 Interventions490 Biomarkers456 Populations648 AI & data176 Industry & policy25

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