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spl-1

Gene

1 paper studies it1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Deutsche Forschungsgemeinschaft and 5 more
  • Model organisms1

Associations

1

Lifespan

mixedin worms1

1 study

  1. spl-1 is associated with lifespan in worms.

    “identify sphingosine phosphate lyase SPL-1/SGPL1 and the ATFS-1-target HOPS complex subunit VPS-39/VPS39 as critical lifespan modulators of micu-1(null) mutant animals”

    Model organismsin micu-1(null) mutant animals

    SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

    Molecular metabolism

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