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PXR

There is 1 paper on PXR in aging research: none in people yet, 1 in animals.

Gene

1 paper studies it1 finding

HGNCNCBI GeneTaxon

See all 1 papers on PXR

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 1 more
  • Animals1

Effects

1

Cognitive function

is required forin mice1

1 study

  1. PXR is required for cognitive function in mice (required for intermittent fasting benefits; shown by PXR blockade in neurons).

    “Blocking its neuronal receptor, pregnane X receptor (PXR), abolished IF's effects.”

    Animalsrequired for intermittent fasting benefits; shown by PXR blockade in neuronsneurons

    Gut microbial-derived indole-3-propionate improves cognitive function in Alzheimer's disease

    Science advances

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