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PPP1R8

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Bijzonder Onderzoeksfonds UGent and 2 more
  • Animals1

Effects

1

Cell cycle regulation

downin mouse cells1

1 study

  1. PPP1R8 inhibits cell cycle regulation in mouse cells.

    “Primary keratinocytes from SKO neonates and human NIPP1-depleted HaCaT keratinocytes failed to proliferate and showed an increase in the expression of cell cycle inhibitors”

    Cellsdepletion in keratinocytes

    Embryonic NIPP1 Depletion in Keratinocytes Triggers a Cell Cycle Arrest and Premature Senescence in Adult Mice

    The Journal of investigative dermatologyFeb 29, 2024

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