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PCLAF

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Effects

1

Cellular senescence

upin mice1

1 study

  1. PCLAF induces cellular senescence in mice.

    “The genetic deletion of PCLAF in macrophages inhibited BMAds senescence and delayed skeletal aging.”

    Animalsgenetic deletion of PCLAF in macrophages

    PCLAF induces bone marrow adipocyte senescence and contributes to skeletal aging

    Bone researchJul 4, 2024

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