PARP10

3 papers3 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: China Postdoctoral Science Foundation and 5 more

Animals2
In silico1

Effects

2

Wnt/β-catenin signalling

upin mice1

1 study

PARP10 activates wnt/β-catenin signalling in mice.
“Upregulated Parp10 inhibited GSK3β, thereby activating pro-regenerative β-catenin signaling.”
Animalsliver
NAT10 deficiency in aging drives impaired liver regeneration by disrupting PARP10 in an ac4C-dependent manner
Clinical and molecular hepatology18 Jun 2026

More on Wnt/β-catenin signalling

GSK3B

downin mice1

1 study

PARP10 inhibits GSK3B in mice.
“Upregulated Parp10 inhibited GSK3β, thereby activating pro-regenerative β-catenin signaling.”
Animalsliver
NAT10 deficiency in aging drives impaired liver regeneration by disrupting PARP10 in an ac4C-dependent manner
Clinical and molecular hepatology18 Jun 2026

Upstream

1

Obsessive-compulsive disorder

downin silico1

1 study

Obsessive-compulsive disorder decreases PARP10 in silico.
“PARP10, CD40, and NDUFS2 were consistently downregulated across all three disorders.”
In silicoin OCD, MDD, and BIP
Disorder-Specific Mitochondrial, Telomere, and Plasticity Signatures Revealed by Cross-Disorder TWAS in OCD, MDD, and Bipolar Disorder
Figshare21 Apr 2026Preprint

More on Obsessive-compulsive disorder

Latest

2 in 12 months

Clinical and Molecular Hepatology19 Jun

NAT10 deficiency in aging drives impaired liver regeneration by disrupting PARP10 in an ac4C-dependent manner

Experiments in miceMechanisms

Figshare21 Apr

Disorder-Specific Mitochondrial, Telomere, and Plasticity Signatures Revealed by Cross-Disorder TWAS in OCD, MDD, and Bipolar Disorder

Preprint: computational studyTelomerase and telomere maintenance

Frontiers in Immunology29 Jun

SARS-CoV-2 infection dysregulates NAD metabolism

Experiments in miceInterventions