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P4H-TMDEFICIENCY

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Animals1

Effects

1

Erythropoietin serum levels

upin mice1

1 study

  1. P4H-TMDEFICIENCY increases erythropoietin serum levels in mice (~2-fold).

    “the resulting ∼2-fold increase in erythropoietin serum levels did not lead to erythrocytosis.”

    AnimalsP4h-tm-/- vs wild-typekidney

    Lack of P4H-TM in mice results in age-related retinal and renal alterations

    Human molecular genetics27 Jul 2016

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