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ORF2

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Dalhousie University and 8 more
  • Humans1

Associations

1

Reverse transcriptase activity

upin humans1

1 study

  1. ORF2 is associated with reverse transcriptase activity in humans.

    “Brain RT activity was higher in the gray matter and correlated with increased neuronal ORF2 expression, further supporting neuronal contributions.”

    Humansin neuronscerebral cortex gray matter

    Sequence Diversity and Encoded Enzymatic Differences of Monocistronic L1 ORF2 mRNA Variants in the Aged Normal and Alzheimer's Disease Brain

    The Journal of neuroscience : the official journal of the Society for Neuroscience15 May 2025

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