Reverse transcriptase activity
1 paper2 findings
- Humans1
Upstream
1Alzheimer's disease
downin humans1
1 study
Alzheimer's disease
downin humans1
Alzheimer's disease decreases reverse transcriptase activity in humans.
“All brains had RT activity, with AD samples showing less activity, consistent with neuronal loss of terminal AD versus aged ND donors.”
Humansterminal AD versus aged ND donorscerebral cortexn = 31
The Journal of neuroscience : the official journal of the Society for Neuroscience15 May 2025
Associations
1ORF2
upin humans1
1 study
ORF2
upin humans1
ORF2 is associated with reverse transcriptase activity in humans.
“Brain RT activity was higher in the gray matter and correlated with increased neuronal ORF2 expression, further supporting neuronal contributions.”
Humansin neuronscerebral cortex gray matter
The Journal of neuroscience : the official journal of the Society for Neuroscience15 May 2025
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