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NSUN5

Gene

2 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Model organisms1
  • Cells1

Effects

2

Cell proliferation

upin human cells1

1 study

  1. NSUN5 increases cell proliferation in human cells.

    “NSUN5 down-expression promoted tumor cell senescence while hindered cell proliferation and migration.”

    Cellsin vitro

    The Oncogenic and Prognostic Significance of NSUN5 in Pan-Cancer and Its Potential roles in Clear Renal Cell Carcinoma

    Research Square14 Mar 2024Preprint

Cellular senescence

downin human cells1

1 study

  1. NSUN5 inhibits cellular senescence in human cells.

    “NSUN5 down-expression promoted tumor cell senescence”

    Cellsin vitro

    The Oncogenic and Prognostic Significance of NSUN5 in Pan-Cancer and Its Potential roles in Clear Renal Cell Carcinoma

    Research Square14 Mar 2024Preprint

More on Cellular senescence

Associations

1

Overall survival

downin humans1

1 study

  1. NSUN5 predicts overall survival in humans.

    “KIRC patients with heightened NSUN5 expression who underwent PD-1 inhibitor exhibited a poorer prognosis.”

    Humansunderwent PD-1 inhibitor

    The Oncogenic and Prognostic Significance of NSUN5 in Pan-Cancer and Its Potential roles in Clear Renal Cell Carcinoma

    Research Square14 Mar 2024Preprint

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