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RCM1

Gene

1 paper1 finding

Taxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Austrian Federal Ministry of Economy, Family and Youth and 7 more
  • 1 of 1 finding with company ties
  • Model organisms1

Effects

1

Lifespan

upin yeast cells1

1 study

  1. RCM1 extends lifespan in yeast cells.

    “Here, we show that reduced levels of the conserved RNA methyltransferase NSUN5 increase the lifespan and stress resistance in yeast, worms and flies.”

    Cellsloss or reduced levels of NSUN5/Rcm1

    Methylation of ribosomal RNA by NSUN5 is a conserved mechanism modulating organismal lifespan

    Nature communications30 Jan 2015

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