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nekl-4

Gene

1 paper1 finding

NCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Institute of General Medical Sciences and 2 more
  • Model organisms1

Effects

1

Ciliary degradation

upin worms1

1 study

  1. nekl-4 increases ciliary degradation in worms.

    “ccpp-1 loss causes age-related ciliary degradation that is suppressed by mutation in the conserved NEK10 homolog nekl-4.”

    Model organismsmutation in nekl-4ciliated sensory neurons

    NEKL-4 regulates microtubule stability and mitochondrial health in C. elegans ciliated neurons

    bioRxiv : the preprint server for biology14 Feb 2024Preprint

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