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NDUFB7

Gene

1 paper1 finding

HGNCNCBI GeneTaxon

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Alexander S. Onassis Public Benefit Foundation and 5 more
  • Animals1

Effects

1

Cysteine overoxidation

downin mice1

1 study

  1. NDUFB7 protects against cysteine overoxidation in mice.

    “In particular, persulfidation of cysteines C80 and C90 in NDUFB7 protects the protein from overoxidation and maintains the complex I activity in cardiomyocytes.”

    Animalsheart

    Loss of cardiac mitochondrial complex I persulfidation impairs NAD⁺ homeostasis in aging

    Redox biology25 Dec 2023

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