MUC1

1. MUC1 has no effect on osteoblast and osteoclast differentiation capacity and activity in mouse cells.

   “No difference was found in osteoclast numbers in vivo and in bone marrow osteoblast or osteoclast differentiation capacity or activity in vitro.”

   CellsMuc1 deletion compared with wild-typebone marrowfemales

   Mucin 1 (Muc1) Deficiency in Female Mice Leads to Temporal Skeletal Changes During Aging

   JBMR plus·Jul 14, 2018

1. MUC1 increases trabecular surface osteoblast numbers in mice.

   “Muc1 deletion results in stiffer femoral bones with fewer osteoblasts lining the trabecular surface”

   Animalsshown by Muc1 deletiontrabecular bonefemales

   Mucin 1 (Muc1) Deficiency in Female Mice Leads to Temporal Skeletal Changes During Aging

   JBMR plus·Jul 14, 2018

More on Trabecular surface osteoblast numbers

1. MUC1 increases trabecular bone volume in mice.

   “deletion of Muc1 results in reduced trabecular bone volume in 8-week-old mice compared with wild-type controls”

   Animalsshown by Muc1 deletion compared with wild-type controlsbonefemales

   Mucin 1 (Muc1) Deficiency in Female Mice Leads to Temporal Skeletal Changes During Aging

   JBMR plus·Jul 14, 2018