Combined gastric microbiome and genetic risk
1 paper studies it4 findings
- Humans1
Associations
4Telomere length
downin humans1
1 study
Telomere length
downin humans1
Combined gastric microbiome and genetic risk is associated with telomere length in humans.
“The individuals having both risks also showed highest degrees of intestinal metaplasia and DNA methylation, and shortest telomere.”
Humanscombined gastric microbiome and genetic riskgastric mucosa
Synergistic effect of gastric microbiome and host genetic factor predispose to gastric cancer
Journal of translational medicineOct 13, 2026
DNA methylation
upin humans1
1 study
DNA methylation
upin humans1
Combined gastric microbiome and genetic risk is associated with DNA methylation in humans.
“The individuals having both risks also showed highest degrees of intestinal metaplasia and DNA methylation, and shortest telomere.”
Humanscombined gastric microbiome and genetic riskgastric mucosa
Synergistic effect of gastric microbiome and host genetic factor predispose to gastric cancer
Journal of translational medicineOct 13, 2026
Intestinal metaplasia
upin humans1
1 study
Intestinal metaplasia
upin humans1
Combined gastric microbiome and genetic risk is associated with intestinal metaplasia in humans.
“The individuals having both risks also showed highest degrees of intestinal metaplasia and DNA methylation, and shortest telomere.”
Humanscombined gastric microbiome and genetic riskgastric mucosa
Synergistic effect of gastric microbiome and host genetic factor predispose to gastric cancer
Journal of translational medicineOct 13, 2026
Gastric cancer
upin humans1OR 23.55
1 study
Gastric cancer
upin humans1OR 23.55
Combined gastric microbiome and genetic risk is associated with gastric cancer in humans (OR 23.55 versus non-cancer; microbiome risk alone OR 11.16; genotype risk alone OR 2.76).
“Individuals possessing the risk of both microbiome and genotype showed significant risk for developing GC with highest OR”
HumansJapanese cohort; combined microbiome and PSCA rs2294008/MUC1 rs4072037 genetic risk versus non-cancergastric mucosan = 620
Synergistic effect of gastric microbiome and host genetic factor predispose to gastric cancer
Journal of translational medicineOct 13, 2026