jmjd-1.2

3 papers1 finding

NCBI Gene Taxon

1 lab in 1 country

Funders: American Heart Association and others

Model organisms3

Effects

1

Lifespan

upin worms1

1 study

jmjd-1.2 extends lifespan in worms.
“gain of function is sufficient to extend lifespan in a UPR(mt)-dependent manner.”
Model organismsgain of function
Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity
CellApr 28, 2016

Latest

The Science of the Total EnvironmentSep 16

6-PPD quinone at environmentally relevant concentrations induced damage on longevity in C. elegans: Mechanistic insight from inhibition in mitochondrial UPR response

Experiments in wormsMitochondrial unfolded protein response

Nature AgingFeb 8

The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress

Experiments in wormsMitochondrial unfolded protein response

CellApr 28

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

Experiments in wormsEpigenetic regulation of gene expression