atfs-1
Gene3 papers2 findingsNCBI Gene 179922Taxon 6239
- Model organisms3
Effects
1Lifespan
is required forin worms2
2 studies
Lifespan
is required forin worms2
atfs-1 is required for lifespan in worms.
Model organismsin Complex I impairment (nuo-6 knockdown)
Divergent Retrograde Signaling Pathways Coordinate Longevity and Metformin Responses in Complex I and Complex IV Deficient C. elegans · bioRxiv : the preprint server for biology · 17 Sep 2026 · Preprint
atfs-1 is required for lifespan in worms.
Model organismsshown by atfs-1 mutant
A Purified Lycii Fructus Polysaccharide Fraction Extends Healthspan in Caenorhabditis elegans with an ATFS-1/UBL-5-Associated Mitochondrial Unfolded Protein Response · Antioxidants (Basel, Switzerland) · 29 Jul 2026
Latest
3USP-48 modulates mitochondrial stress and enables longevity in low-insulin worms
A genome-wide screen in roundworms links histone H2B deubiquitination by USP-48 to mitochondrial stress signaling and extended lifespan.A genome-wide screen in roundworms links histone H2B deubiquitination by USP-48 to mitochondrial stress signaling and extended lifespan.